Unlike a manuscript, posters can (and should!) adopt a variety of layouts depending on the form of charts and photographs. As long as you maintain sufficient white space, keep column alignments logical, and provide clear cues to your readers how they should "travel" through your poster elements, you can get creative. Make your poster creative! As an example (illustrated below), perhaps you might want to demote the unimportant sections (that few people read) to the undesirable real estate at the bottom portion of your poster, freeing up the right-hand column area for your stunning Conclusions. This strategy might be especially valuable for portrait-style posters where the bottom part of the paper almost touches the floor.
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Thanks to BoingBoing.